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Ketamine is usually given intravenously, which is the fastest way to get the drug into the brain. Most people start with about six doses over a 1 to 2 week period and then take booster IV every 3-5 weeks. You may need to continue treatment for a year or more to see long-term results.
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Researchers aren't sure exactly how ketamine works to treat depression, but they have a few ideas. Unlike antidepressants, which work by altering the balance of brain chemicals like serotonin and dopamine, ketamine is thought to alter the way brain cells communicate with each other. “If you look at it in computer terms, what ketamine does is a hardware solution - not like antidepressants, which are like a software solution,” says Glen Brooks, MD, anesthesiologist and medical director of NY Ketamine Infusions.
How much does Ketamine cost ?
The price may vary depending on the doctor and the location. Typically, each IV costs between $ 400 and $ 800. Often the insurance does not cover the cost.
Why isn't ketamine FDA-approved to treat depression?
To approve a new drug, the FDA needs proof that it works and doesn't cause major harm. The FDA draws this evidence from clinical trials involving hundreds or thousands of people. Most of the studies done on ketamine to date have been small, involving only 25 to 50 people.